[D-Ser14]-Humanin_product_DataBase

Bioactivity	[D-Ser14]-Humanin is a bioactive peptide in which the Ser14 residue of Humanin (HY-P1928) is changed from L-form to D-form. [D-Ser14]-Humanin has potent inhibitory activity against the fibrillation of amyloid-β. Humanin (HY-P1928) inhibits the aging-related death of various cells caused by amyloid fibrils and oxidative stress, and [D-Ser14]-Humanin has better cell protection activity than Humanin (HY-P1928). [D-Ser14]-Humanin can be used in the study of Alzheimer's disease[1].
CAS	570382-85-3
Sequence	Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-{d-Ser}-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala
Shortening	MAPRGFSCLLLLT-{d-Ser}-EIDLPVKRRA
Formula	C119H204N34O32S2
Molar Mass	2687.23
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Alsanousi, et al. "Solution NMR structure and inhibitory effect against amyloid-β fibrillation of Humanin containing a d-isomerized serine residue." Biochemical and biophysical research communications 477.4 (2016): 647-653.

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